Endocrine Cell Clustering During Human Pancreas Development
نویسندگان
چکیده
منابع مشابه
Development of the endocrine pancreas.
This short review presents the recent breakthroughts in our understanding of the important steps controlling pancreas morphogenesis and differentiation, and on the transcription factors regulating pancreas organogenesis and islet cell differentiation and involved in the specification of the beta and alpha cell lineages. All these studies should permit a comprehensive view of the full genetic pr...
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Knowledge of human pancreas development underpins our interpretation and exploitation of human pluripotent stem cell (PSC) differentiation toward a β-cell fate. However, almost no information exists on the early events of human pancreatic specification in the distal foregut, bud formation, and early development. Here, we have studied the expression profiles of key lineage-specific markers to un...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2009
ISSN: 0022-1554,1551-5044
DOI: 10.1369/jhc.2009.953307